
Life Science Buffers
Balanced salt solutions and powders used for molecular, protein, nucleic acid, and cell biology applications including cell culture, electrophoresis, ELISA, and chromatography processes; available in a variety of formulations and grades.
Buffer solutions serve to keep pH (acidity or alkalinity) nearly constant in a variety of chemical and biological applications. For example, a bicarbonate buffer helps maintain the pH of blood, a buffered saline maintains cellular contents at a consistent pH level, and buffers help maintain a narrow pH range for enzymes to function correctly.
Most biological samples used in research are kept at a pH of about 7.4. Common biological buffers used for tissue culture include Dulbeccos phosphate buffered saline (PBS), Tris base, HEPES, MOPS, PIPES, and other formulations developed for specific cell lines or applications. Most buffers used in cell culture are also DNase-, RNase-, and protease-free.
The choice of buffer for a particular biological reaction or site depends on several factors:
- Temperature
- Desired or target pH
- Buffer toxicity (to the system)
- Buffer interactions with other system components
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Filtered Search Results

Gibco™ PBS, pH 7.4
Gibco PBS, pH 7.4, is a balanced salt solution ideal for cell culture applications. It lacks calcium, magnesium, and phenol red, preventing cell adhesion and assay interference. Trusted for quality, Gibco PBS ensures reliable results in cell washing, transport, and reagent preparation.

Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Physical Form | Liquid |
---|---|
pH | 7.3 to 7.5 |
Manufacturing Quality | cGMP-compliant under the ISO 13485 standard |
Chemical Name or Material | Phosphate Buffered Saline (PBS) |
Recommended Storage | 15°C to 30°C |
Concentration | 1 X |
For Use With (Application) | Mammalian Cell Culture |
Osmolality | 280 - 315 mOsm/kg |
Sterility | Sterile-filtered |
MOPSO Sodium Salt, MP Biomedicals™
CAS: 79803-73-9 Molecular Formula: C7H14NNaO5S Molecular Weight (g/mol): 247.24 InChI Key: WSFQLUVWDKCYSW-UHFFFAOYNA-M IUPAC Name: sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate SMILES: [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O
CAS | 79803-73-9 |
---|---|
Molecular Weight (g/mol) | 247.24 |
SMILES | [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O |
IUPAC Name | sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate |
InChI Key | WSFQLUVWDKCYSW-UHFFFAOYNA-M |
Molecular Formula | C7H14NNaO5S |
Tris, Cell Culture Reagent, ≥99.95%, MP Biomedicals™
Tris, Cell Culture Reagent, ≥99.95% is a biological buffer for various applications.
MilliporeSigma™ MES, Sodium Salt, ULTROL™ Grade, Calbiochem™,
CAS: 71119-23-8 Molecular Formula: C6H12NNaO4S Molecular Weight (g/mol): 217.215 InChI Key: IRHWMYKYLWNHTL-UHFFFAOYSA-M Synonym: 2-(N-Morpholino)ethanesulfonic Acid, Na PubChem CID: 23673676 ChEBI: CHEBI:62955 IUPAC Name: sodium;2-morpholin-4-ylethanesulfonate SMILES: C1COCCN1CCS(=O)(=O)[O-].[Na+]
PubChem CID | 23673676 |
---|---|
CAS | 71119-23-8 |
Molecular Weight (g/mol) | 217.215 |
ChEBI | CHEBI:62955 |
SMILES | C1COCCN1CCS(=O)(=O)[O-].[Na+] |
Synonym | 2-(N-Morpholino)ethanesulfonic Acid, Na |
IUPAC Name | sodium;2-morpholin-4-ylethanesulfonate |
InChI Key | IRHWMYKYLWNHTL-UHFFFAOYSA-M |
Molecular Formula | C6H12NNaO4S |
MilliporeSigma™ MOPS, Free Acid, ULTROL™ Grade, Calbiochem™,
CAS: 1132-61-2 Molecular Formula: C7H15NO4S Molecular Weight (g/mol): 209.26 MDL Number: MFCD00006183 InChI Key: DVLFYONBTKHTER-UHFFFAOYSA-N Synonym: 3-(N-Morpholino)propanesulfonic Acid PubChem CID: 70807 ChEBI: CHEBI:44115 IUPAC Name: 4-(3-sulfonatopropyl)morpholin-4-ium SMILES: [O-]S(=O)(=O)CCC[NH+]1CCOCC1
PubChem CID | 70807 |
---|---|
CAS | 1132-61-2 |
Molecular Weight (g/mol) | 209.26 |
ChEBI | CHEBI:44115 |
MDL Number | MFCD00006183 |
SMILES | [O-]S(=O)(=O)CCC[NH+]1CCOCC1 |
Synonym | 3-(N-Morpholino)propanesulfonic Acid |
IUPAC Name | 4-(3-sulfonatopropyl)morpholin-4-ium |
InChI Key | DVLFYONBTKHTER-UHFFFAOYSA-N |
Molecular Formula | C7H15NO4S |
Invitrogen™ xMAP Sheath Fluid Plus
xMAP Sheath Fluid Plus is the delivery medium that carries the sample to the optics component of Luminex xMAP technology-based instruments

Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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MilliporeSigma™ MOPS, Free Acid, Molecular Biology Grade, Calbiochem™,
CAS: 1132-61-2 Molecular Formula: C7H15NO4S Molecular Weight (g/mol): 209.26 MDL Number: MFCD00006183 InChI Key: DVLFYONBTKHTER-UHFFFAOYSA-N Synonym: 3-(N-Morpholino)propanesulfonic Acid PubChem CID: 70807 ChEBI: CHEBI:44115 IUPAC Name: 4-(3-sulfonatopropyl)morpholin-4-ium SMILES: [O-]S(=O)(=O)CCC[NH+]1CCOCC1
PubChem CID | 70807 |
---|---|
CAS | 1132-61-2 |
Molecular Weight (g/mol) | 209.26 |
ChEBI | CHEBI:44115 |
MDL Number | MFCD00006183 |
SMILES | [O-]S(=O)(=O)CCC[NH+]1CCOCC1 |
Synonym | 3-(N-Morpholino)propanesulfonic Acid |
IUPAC Name | 4-(3-sulfonatopropyl)morpholin-4-ium |
InChI Key | DVLFYONBTKHTER-UHFFFAOYSA-N |
Molecular Formula | C7H15NO4S |
BES, 99+%, MP Biomedicals™
CAS: 10191-18-1 Molecular Formula: C6H15NO5S Molecular Weight (g/mol): 213.25 MDL Number: MFCD00007533 InChI Key: AJTVSSFTXWNIRG-UHFFFAOYSA-N Synonym: n,n-bis 2-hydroxyethyl-2-aminoethanesulfonic acid,bes,ethanesulfonic acid, 2-bis 2-hydroxyethyl amino,2-bis 2-hydroxyethyl amino ethanesulfonic acid,n,n-bis 2-hydroxyethyl taurine,n,n-bis hydroxyethyl-2-aminoethanesulfonic acid,bes buffering agent,taurine, n,n-bis 2-hydroxyethyl,2-bis 2-hydroxyethyl amino-ethanesulfonicacid PubChem CID: 73243 ChEBI: CHEBI:39045 IUPAC Name: 2-[bis(2-hydroxyethyl)amino]ethane-1-sulfonic acid SMILES: OCCN(CCO)CCS(O)(=O)=O
PubChem CID | 73243 |
---|---|
CAS | 10191-18-1 |
Molecular Weight (g/mol) | 213.25 |
ChEBI | CHEBI:39045 |
MDL Number | MFCD00007533 |
SMILES | OCCN(CCO)CCS(O)(=O)=O |
Synonym | n,n-bis 2-hydroxyethyl-2-aminoethanesulfonic acid,bes,ethanesulfonic acid, 2-bis 2-hydroxyethyl amino,2-bis 2-hydroxyethyl amino ethanesulfonic acid,n,n-bis 2-hydroxyethyl taurine,n,n-bis hydroxyethyl-2-aminoethanesulfonic acid,bes buffering agent,taurine, n,n-bis 2-hydroxyethyl,2-bis 2-hydroxyethyl amino-ethanesulfonicacid |
IUPAC Name | 2-[bis(2-hydroxyethyl)amino]ethane-1-sulfonic acid |
InChI Key | AJTVSSFTXWNIRG-UHFFFAOYSA-N |
Molecular Formula | C6H15NO5S |
bis-Tris, ≥99%, MP Biomedicals™
CAS: 6976-37-0 Molecular Formula: C8H19NO5 Molecular Weight (g/mol): 209.242 InChI Key: OWMVSZAMULFTJU-UHFFFAOYSA-N PubChem CID: 81462 ChEBI: CHEBI:41250 IUPAC Name: 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol SMILES: C(CO)N(CCO)C(CO)(CO)CO
PubChem CID | 81462 |
---|---|
CAS | 6976-37-0 |
Molecular Weight (g/mol) | 209.242 |
ChEBI | CHEBI:41250 |
SMILES | C(CO)N(CCO)C(CO)(CO)CO |
IUPAC Name | 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol |
InChI Key | OWMVSZAMULFTJU-UHFFFAOYSA-N |
Molecular Formula | C8H19NO5 |
TRIS, MP Biomedicals™
CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.14 MDL Number: MFCD00004679 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N Synonym: Tris-[hydroxymethyl]aminomethane,THAM, 2-Amino-2-(hydroxymethyl)- 1,3-propandiol,Tromethamine,Trometamol
CAS | 77-86-1 |
---|---|
Molecular Weight (g/mol) | 121.14 |
MDL Number | MFCD00004679 |
Synonym | Tris-[hydroxymethyl]aminomethane,THAM, 2-Amino-2-(hydroxymethyl)- 1,3-propandiol,Tromethamine,Trometamol |
InChI Key | LENZDBCJOHFCAS-UHFFFAOYSA-N |
Molecular Formula | C4H11NO3 |
Hanks' Balanced Salts, Without Sodium Bicarbonate, MP Biomedicals™
Hanks' Balanced Salts, Without Sodium Bicarbonate, Orange Powder
Color | Orange |
---|---|
Physical Form | Powder |
pH | 6.0 to 7.0 (before adjustment with sodium bicarbonate) |
MP Biomedicals™ 1X Hanks' Balanced Salt Solution (Modified) without Phenol Red
1X Hanks' Balanced Salt Solution (Modified) without Phenol Red is a clear medium ideal for working with stem cells or when growing cells at low densities.